Abu ZahidRangpur Medical College, Bangladesh
Title: Mycobacterium Endocarditis: A rare case
Mycobacterium Endocarditis is a very rare case. Endocarditis is referred to as the infection in the endocardium, the inner lining of the heart chambers and heart valves. Infective Endocarditis is associated with substantial morbidity & mortality. Several published studies have reported in-hospital mortality of 15 percent to 20 percent and 1-year mortality of 40 percent. In the United States alone, approximately 15,000 new cases of infective Endocarditis are diagnosed each year. The organism itself is exceptionally resistant to conventional antibiotics, requiring a particular combination of antibiotics (e.g., Isoniazid, Rifampin, Ethambutol, Pyrazinamide). The treatment duration can last for months. Mycobacterium Tuberculosis yet remains a global threat being a major cause of death. It has the potential to infect every organ of the body including heart. The very first cases of Tuberculous Endocarditis (TBE) were reported in 1892. Afterward, many other cases have been described, highlighting the significant morbidity and mortality associated with this manifestation of TB. TBE usually presents with miliary tuberculosis and most early cases were diagnosed on autopsy. Granulomas caused by Mycobacterium Tuberculosis have been observed at autopsy in heart, predominantly in the myocardium and endocardium, but rarely involving the coronary vessels and valvular structures. With the increasing application of prosthetic valve replacements in the treatment of Infective Endocarditis (IE), TB infections have begun to affect these as well as native valves. With the introduction of TB culture methods and drug therapy, the prognosis has improved. The rarity of this disease and the resistance of the bacteria and treatment duration makes it difficult to treat disease with a high mortality rate.
Md Abu Zahid completed his MD (Cardiology) in 2012. He is a life member of Bangladesh Cardiac Society and also a life member of Bangladesh society of Cardiovascular and intervention(BSCI) . He is a member of ACC (American College of Cardiology), also a member of ACP and ESC. He is an Assistant Professor of Cardiology Department, Rangpur Medical College, Bangladesh. He has over 20 publications, several book chapters and attended more than 50 conferences . He has a large research work on Heart Failure, Hypertension, Dyslipidaemia . Presently he is working on the field of advanced HF and also on Interventional Cardiology