
Ermal Likaj
University Hospital Center “Mother Theresa”, AlbaniaTitle: Surgical treatment of infective endocarditis in hemodialysis patients
Abstract
Patients who have chronic kidney disease or are receiving dialysis
therapy are at high risk of infection, related hospitalization, and mortality. IE in patients receiving chronic hemodialysis is a very frequent
occurrence. Infective endocarditis (IE) is a
life-threatening infection that contributes to significant morbidity and death
in patients undergoing dialysis. Compared with the general population, patients
undergoing dialysis are more vulnerable to IE because of their impaired
immunity, high prevalence of periodontal disorders, frequent vascular
cannulation, and repetitive exposure to non-physiologic dialysates. The diagnosis is complex and its presence should be considered in all
hemodialysis patients with bacteremia. Among the general population, surgical indications for IE are clear with
a moderate level of evidence. In patients on dialysis, however, the level of
evidence is low, and recommendations are weak. Patients undergoing dialysis have
more comorbidities and higher perioperative complication risks than the general
population. The Society of Thoracic Surgery score and EURO score both
incorporate kidney function. Impaired kidney function or dialysis is a strong
predictor of short-term mortality. Because of the high perioperative risk,
patients on dialysis who develop IE undergo surgical intervention less
frequently than patients with IE and without kidney diseases. Thus, evidence to
support the benefit of surgery in such patients is lacking, and the decision
regarding whether to perform surgery to treat IE continues to be made on a
case-by-case basis.
Biography
TBA