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Mariya Tabassum

Abdul Malek Ukil Medical College, Bangladesh

Title: Visceral Adiposity Index (VAI): A Novel Criterion for Diagnosing Metabolic Obesity in Normal-weight Bangladeshi Adults

Abstract

“Metabolic Obesity” is defined as the presence of metabolic syndrome in an individual, irrespective of his/her BMI (Body Mass Index). Some normal-weight individuals are susceptible to cardiovascular diseases like overweight and obese individuals, as a consequence of insulin resistance & atherogenic dyslipidemia. Distribution of visceral fat has a strong correlation with the development of insulin resistance & dyslipidemia. But BMI does not take visceral fat distribution into account. So BMI, alone, is no longer a reliable indicator of cardiometabolic abnormalities. Visceral Adiposity Index (VAI) is a measure of visceral fat distribution & insulin sensitivity. It is a gender-specific, mathematical formula, comprising both anthropometric (BMI & waist circumference) & biochemical parameters (serum Triglyceride & HDL-C).
Aim: This study aims to assess the performance of VAI as a new criterion for detecting metabolic obesity.
Study Design & Methods: 100 healthy and normal-weight adults from 19 to 45 years of age were recruited for this cross-sectional study. Anthropometric measurements & blood pressures of the study subjects were recorded in preformed data sheets. Fasting blood Glucose, serum Triglyceride & serum HDL-C concentrations were estimated. Study subjects were classified into “Metabolically Healthy Normal-weight (MHNW)” & “Metabolically Obese Normalweight (MONW)” phenotypes according to presence or absence of metabolic syndrome respectively.
Results: 33.00% of the subjects were “Metabolically Obese”, according to criteria. Area under the curve (AUC) value of VAI, obtained from Receiver Operating Characteristic (ROC) curve analysis, in total study subjects was 0.9 (p Value = 0.000). Sensitivity, Specificity, Positive Predictive Value & Negative Predictive Value of VAI as diagnostic criterion in male study subjects were 70.32%, 77.88%, 70.93% & 76.32% respectively. Sensitivity, Specificity, Positive Predictive Value & Negative Predictive Value of VAI as diagnostic criterion in female study subjects were 70.45%, 97.32%, 86.96% & 61.58% respectively. Sensitivity, Specificity, Positive Predictive Value & Negative Predictive Value of VAI as diagnostic criterion in total study subjects were 92.05%, 75.00%, 74.31% & 92.31% respectively. 54.00% of the total study subjects were “Metabolically Obese”, based on the cutoff value of VAI.
Conclusion: Therefore, VAI is appropriate as a novel criterion for diagnosing metabolic obesity in normal-weight Bangladeshi Adults

Biography

TBA