Medvedenko Igor VSouth Ural State Medical University, Russian Federation
Title: Kidney disfunction frequency in patients with cardiomyopathy
Kidney disfunction is a risk factor for cardiovascular morbidity and mortality. The study of the relationship between cardiomyopathies (CMP) and kidneys in the cardiorenal continuum is extremely relevant for the primary and secondary prevention of these diseases. The study included 695 medical records of patients admitted to the hospital with a diagnosis of cardiomyopathy with ciphers according to the ICD X revision: I42.0; I42.1 – I42.2; I40.0 – I40.9; I41.0 – I41.1; I42.6; I25.5; I42.8 – I42.9. Glomerular filtration rate (GFR) was determined using the CKD Epidemiology Collaboration 2009 formula. Among the patients with CMP, there were more men than women: 433 (62.2%) men and 262 (37.8%) women (p<0.001). The average age of men in comparison with the age of women was less -56.4±14.4 years and 65.5±14.1 years (p=0.001). Decreased GFR (<60 ml\min\1.73 m2) was detected in 254 (36.5%) people out of 695 people with CMP, among them there were no significant differences by gender: 156 (36.0%) people among men (n=433), 98 (37.4%) women (n=262) (p>0.5). In individuals with low GFR (n=254) with the same nosological forms of CMP of the same age, no differences in GFR were also obtained (p>0.5). A significant decrease in GFR was observed only in men in the age group of 50-59 years with dilated cardiomyopathy - 58.9±21.2 ml\min\1.73 m2 (p=0.025) and in the age group of 60- 69 years with ischemic cardiomyopathy –52.2+20.6 ml\min\1.73 m2 (p=0.03). Conclusions. Low GFR in the group of patients with CMP is registered in 36.5% of people without obvious gender differences. Among the nosological forms of CMP, men with dilated CMP and ischemic CMP aged 50 to 69 years had a significant decrease in GFR.
Medvedenko Igor Vladimirovich - cardiologist, postgraduate student of the Department of Clinical Pharmacology and Therapy of the South Ural State Medical University of the Ministry of Health of the Russian Federation, Chelyabinsk city. Applicant for the scientific degree of candidate of medical sciences. He has five publications on the research topic