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Rabindra Nath Das
The University of Burdwan, IndiaTitle: Relationship of mean arterial pressure with other cardiac and biological factors
Abstract
Objectives: The
relationship of mean arterial pressure (MAP) with the other cardiac and
biological factors is very complicated, which is not well-known in the
literature. The report focuses on the
associations of MAP with the other cardiac and biological factors for shock
patients.
Material & Methods:
A real data set of 113 shock patients with 20 study variables is considered in
the report, which is available in the site http://www.umass.edu/statdata/statdata/data/shock.txt
The probabilistic
model of MAP has been derived using statistical joint generalized linear
models.
Results: The MAP is positively associated with age
(P=0.0065), systolic blood pressure (SBP) (P<0.0001), diastolic blood pressure (DBP) (P<0.0001), cardiac index (CI)
(P<0.0001), joint interaction effects of heart rate (HR) & mean central
venous pressure (MCVP) (HR*MCVP) (P=0.0288), DBP*MCVP (P=0.0022), body surface
index (BSI)*MCVP (P=0.0337), SBP*BSI (P=0.0472), while it is negatively
associated with survival status (Survive) (P=0.0127), MCVP (P=0.0004), BSI
(P=0.0048), appearance time (AT) (P=0.0379),
hematocrit (HCT) (P=0.0988), SBP*HR
(P=0.0039) and SBP*DBP
(P<0.0001). Variance of MAP is negatively associated with sex (P=0.0279),
shock type at level 2 (P=0.0367), at level 3 (P=0.0012), SBP (P=0.0342), DBP
(P<0.0001), BSI (P<0.0001), DBP*MCVP (P=0.0482), while it is positively
associated with SBP*DBP
(P=0.0004), DBP*BSI (P<0.0001) and HCT
(P=0.0703).
Conclusion: MAP
is higher at older ages. It increases if SBP, or DBP, or CI, or HR*MCVP, or
DBP*MCVP, or MCVP*BSI, or SBP*BSI increases. It decreases if MCVP, or BSI, or
AT, or HCT, or SBP*HR, or SBP*DBP increases.
Biography
TBA