Virtual Conference

Rabindra Nath Das

The University of Burdwan, India

Title: Relationship of mean arterial pressure with other cardiac and biological factors


Objectives: The relationship of mean arterial pressure (MAP) with the other cardiac and biological factors is very complicated, which is not well-known in the literature.  The report focuses on the associations of MAP with the other cardiac and biological factors for shock patients.
Material & Methods: A real data set of 113 shock patients with 20 study variables is considered in the report, which is available in the site  The probabilistic model of MAP has been derived using statistical joint generalized linear models. 
Results: The MAP is positively associated with age (P=0.0065), systolic blood pressure (SBP) (P<0.0001), diastolic blood pressure (DBP) (P<0.0001), cardiac index (CI) (P<0.0001), joint interaction effects of heart rate (HR) & mean central venous pressure (MCVP) (HR*MCVP) (P=0.0288), DBP*MCVP (P=0.0022), body surface index (BSI)*MCVP (P=0.0337), SBP*BSI (P=0.0472), while it is negatively associated with survival status (Survive) (P=0.0127), MCVP (P=0.0004), BSI (P=0.0048), appearance time (AT) (P=0.0379),   hematocrit (HCT) (P=0.0988), SBP*HR  (P=0.0039) and  SBP*DBP (P<0.0001). Variance of MAP is negatively associated with sex (P=0.0279), shock type at level 2 (P=0.0367), at level 3 (P=0.0012), SBP (P=0.0342), DBP (P<0.0001), BSI (P<0.0001), DBP*MCVP (P=0.0482), while it is positively associated with SBP*DBP (P=0.0004), DBP*BSI (P<0.0001) and HCT (P=0.0703). 
Conclusion: MAP is higher at older ages. It increases if SBP, or DBP, or CI, or HR*MCVP, or DBP*MCVP, or MCVP*BSI, or SBP*BSI increases. It decreases if MCVP, or BSI, or AT, or HCT, or SBP*HR, or SBP*DBP increases.