GLOBAL SUMMIT ON CARDIOLOGY AND CARDIO CARE
NOVEMBER 30- DECEMBER 01, 2023 | DUBAI, UAE
Theme: Research Trends and Advances in Cardiology
Ysabel Cecilia López-Aldazoro
Clínica San Miguel, SpainTitle: Atrial septal aneurysm in identical twins
Abstract
Introduction: Interatrial septal aneurysm (ISA)
is a dilatation of saccular tissue, generally located in the foramen ovale
area, which moves freely and protrudes into the right or left atrium, or even
both. Today it is estimated that 85% of children born with congenital heart
disease survive to adulthood, however, we have not found cases of ISA reported
in identical twins in adulthood.
Methods: Two 55-year-old female patients, identical twins (EAM and RAM), height, 69 and 70.25 ins., weight, 164 and 145 lbs., body surface area, 1,899 and 1,826 m2 respectively, consulted for elevated blood pressure (160/90 and 160/95 mmHg respectively). One of them reported headache accompanied by joint pain and mild dyspnea, the other patient reported palpitations and mild dizziness. His parents are hypertensive. They were hospitalized at 5 months of age due to viral meningitis, with no further consequences. Antihypertensive treatment, laboratory, stress test, and echocardiogram/Doppler were prescribed.
Results: Laboratory tests were found to be
normal. The stress test (protocol: Bruce) was reported to be negative for
induced myocardial ischemia. The echocardiographic / Doppler results are
observed in table # 1 and figure # 1-4.
Conclusions:
Twins, particularly monochorionic twins, are at increased risk of congenital
anomalies compared with singleton pregnancies, and the risk of cerebrovascular
disease (CVD) or transient ischemic attack (TIA) in patients with ISA is 6.7%
in adult patients. ISA has been associated with acquired cardiac diseases, such
as valvular heart disease, cardiomyopathies, pulmonary and systemic
hypertension, ischemic heart disease, arrhythmias, and thrombus formation. More
recently, an association with embolic cerebrovascular pathology has been
observed, both in TIA and CVD. For this reason, we consider that in adult
patients who are identical twins when one of them is found with ISA, an
evaluation should be carried out in their twin for its appropriate treatment
and thus avoid future cardiovascular complications derived from this anomaly.
According to our reviews, this is the first case of ISA in identical twins. New
observations on ISA in twins are needed.
Biography
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