Varsha Jagdish Galani
Indubhai Patel College of Pharmacy and Research Centre, IndiaPresentation Title:
Coronary mysteries: Understanding MINOCA and CAD in myocardial infarction patients
Abstract
The clinical characteristics of myocardial infarction with non-obstructive coronary artery disease (MINOCA) versus obstructive coronary artery disease (MICAD) remain poorly defined. This study aimed to compare the prevalence, treatments, and outcomes of these conditions. A retrospective record-based study was conducted using data from 363 acute myocardial infarction patients at Tulip Heart Centre, Anand, Gujarat, India. Data included demographic details, medical history, diagnostic results, treatment practices, and outcomes. MINOCA was found in 4.4% of patients, while MICAD was present in 27.52%. MINOCA patients were younger (56.8 years vs. 60.6 years) and more likely to be female compared to MICAD patients (47.17% vs. 30.65%). Both conditions were more common in men, but women were more likely to present with MINOCA. There were no significant differences in clinical presentation or risk factors between the two groups. MINOCA patients had lower levels of ST elevation MI and cardiac biomarkers (47.16% vs. 87.72%) compared to MICAD patients. Proportions of good 2D echocardiography reports (47.17% vs. 23.55%) and LVEF ≥ 55 (49.01% vs. 23.05%) were higher in the MINOCA group. Standard medications were prescribed less frequently to MINOCA patients. Mortality and rehospitaliz-ation rates were higher in MICAD patients. MINOCA requires targeted therapy based on its underlying pathogenesis. The study highlights significant differences in prevalence, clinical presentation, and outcomes between MINOCA and MICAD patients.
Biography
Varsha Galani is a pharmacologist currently working as a Professor in Indubhai Patel College of Pharmacy and Research Centre, affiliated with Gujarat Technological University, Gujarat (India). She had pursued her B.Pharm, M. Pharm and Ph.D degrees from Gujarat, India. She has total 24 years of teaching experience. She has published 45 research papers and 14 reviews in various international journals. She worked as a reviewer and editorial board member in many international journals. She had guided 24 M. Pharm students in pharmacology and clinical pharmacy. She had received grant from government of Gujarat for one research project. She has established neuropharmacological activity, analgesic activity, anti-inflammatory activity, antidepressant activity, antistress activity, antianxiety activity, antinephrolitiatic activity, antiulcer activity etc. of different Indian medicinal plants using various ethanopharmacological experimental models. Her area of work in the clinical field are Epidemiology study, Case control hospital based study, Bioequivalence study, Cancer research, Drug interaction study etc. She had delivered research work in many scientific programmes.
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